Article
Functionally distinct nucleosome-free regions in yeast require Rad7 and Rad16 for nucleotide excision repair.
DNA repair - 3 May 2008
Lettieri Teresa, Kraehenbuehl Rolf, Capiaghi Christoph, Livingstone-Zatchej Magdalena, Thoma Fritz
Abstract excerpt
In yeast, Rad7 and Rad16 are two proteins required for nucleotide excision repair (NER) of non-transcribed chromatin. They have roles in damage recognition, in the postincision steps of NER, and in ultraviolet-light-dependent histone H3 acetylation. Moreover, Rad16 is an ATP-ase of the SNF2 superfamily and therefore might facilitate chromatin repair by nucleosome remodelling. Here, we used yeast rad7 Delta rad16...
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