Article
DNA repair gene RAD3 of S. cerevisiae is essential for transcription by RNA polymerase II.
Nature - 6 Jan 1994
Guzder S N, Qiu H, Sommers C H, Sung P, Prakash L, Prakash S
Abstract excerpt
The RAD3 gene of Saccharomyces cerevisiae is required for excision repair of ultraviolet-damaged DNA and is essential for cell viability. The RAD3-encoded protein shares a high degree of homology with the human ERCC2(XPD) gene product. Mutations in XPD, besides causing the cancer-prone syndrome x...
Topics
- Adenosine Triphosphatases
- Base Sequence
- DNA
- DNA Helicases
- DNA Repair
- DNA-Binding Proteins
- Genes, Fungal
- Genes, Lethal
- Genes, Recessive
- Humans
- Molecular Sequence Data
- Mutation
- Proteins
- RNA Polymerase II
- RNA, Messenger
- RNA, Transfer, Amino Acyl
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins