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Article

A role for checkpoint kinase-dependent Rad26 phosphorylation in transcription-coupled DNA repair in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Jan 2010

Taschner Michael, Harreman Michelle, Teng Yumin, Gill Hefin, Anindya Roy, Maslen Sarah L, Skehel J Mark, Waters Raymond, Svejstrup Jesper Q

Abstract excerpt

Upon DNA damage, eukaryotic cells activate a conserved signal transduction cascade known as the DNA damage checkpoint (DDC). We investigated the influence of DDC kinases on nucleotide excision repair (NER) in Saccharomyces cerevisiae and found that repair of both strands of an active gene is affected by Mec1 but not by the downstream checkpoint kinases, Rad53 and Chk1. Repair of the nontranscribed strand (by...

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Source

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Identifiers

PMID: 19901073
DOI: 10.1128/MCB.00822-09
PMCID: PMC2798469

Genes

DDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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