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Article

A family-based association study of DIO2 and children mental retardation in the Qinba region of China.

Journal of human genetics - 1 Jan 2012

Zhang Kejin, Xi Heng, Wang Xiying, Guo Yale, Huang Shaoping, Zheng Zijian, Zhang Fuchang, Gao Xiaocai

Abstract excerpt

Deiodinase enzyme II (DIO2) has an important role in individuals' thyroid hormones' level, the development of central and peripheral nervous systems and characterized by mental retardation (MR). The DIO2 gene was genotyped by using five haplotype-tagging single-nucleotide polymorphisms (SNPs) in 157 Chinese MR high-density family pedigrees, including 452 nuclear families and >1460 persons. The single marker and...

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Identifiers

PMID: 22048657
DOI: 10.1038/jhg.2011.121

Genes

DIO2

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A family-based association study of DIO2 and children mental retardation in the Qinba region of China.PMID 22048657Read ↗

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