Article
Structural mechanisms of inactivation in scabies mite serine protease paralogues.
Journal of molecular biology - 24 Jul 2009
Fischer Katja, Langendorf Christopher G, Irving James A, Reynolds Simone, Willis Charlene, Beckham Simone, Law Ruby H P, Yang Sundy, Bashtannyk-Puhalovich Tanya A, McGowan Sheena, Whisstock James C, Pike Robert N, Kemp David J, Buckle Ashley M
Abstract excerpt
The scabies mite (Sarcoptes scabiei) is a parasite responsible for major morbidity in disadvantaged communities and immuno-compromised patients worldwide. In addition to the physical discomfort caused by the disease, scabies infestations facilitate infection by Streptococcal species via skin lesions, resulting in a high prevalence of rheumatic fever/heart disease in affected communities. The scabies mite produces...
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