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Article

Scabies mite inactive serine proteases are potent inhibitors of the human complement lectin pathway.

PLoS neglected tropical diseases - 1 May 2014

Reynolds Simone L, Pike Robert N, Mika Angela, Blom Anna M, Hofmann Andreas, Wijeyewickrema Lakshmi C, Kemp Dave, Fischer Katja

Abstract excerpt

Scabies is an infectious skin disease caused by the mite Sarcoptes scabiei and has been classified as one of the six most prevalent epidermal parasitic skin diseases infecting populations living in poverty by the World Health Organisation. The role of the complement system, a pivotal component of human innate immunity, as an important defence against invading pathogens has been well documented and many parasites...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24854034
DOI: 10.1371/journal.pntd.0002872
PMCID: PMC4031079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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