Article
Centrocortin cooperates with centrosomin to organize Drosophila embryonic cleavage furrows.
Current biology : CB - 9 Jun 2009
Kao Ling-Rong, Megraw Timothy L
Abstract excerpt
In the Drosophila early embryo, the centrosome coordinates assembly of cleavage furrows. Currently, the molecular pathway that links the centrosome and the cortical microfilaments is unknown. In centrosomin (cnn) mutants, in which the centriole forms but the centrosome pericentriolar material (PCM) fails to assemble, actin microfilaments are not organized into furrows at the syncytial cortex [6]. Although CNN is...
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