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Article

The centrosomin protein is required for centrosome assembly and function during cleavage in Drosophila.

Development (Cambridge, England) - 1 Jul 1999

Megraw T L, Li K, Kao L R, Kaufman T C

Abstract excerpt

Centrosomin is a 150 kDa centrosomal protein of Drosophila melanogaster. To study the function of Centrosomin in the centrosome, we have recovered mutations that are viable but male and female sterile (cnnmfs). We have shown that these alleles (1, 2, 3, 7, 8 and hk21) induce a maternal effect on early embryogenesis and result in the accumulation of low or undetectable levels of Centrosomin in the centrosomes of...

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Identifiers

PMID: 10357928
DOI: 10.1242/dev.126.13.2829

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