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Article

Characterization of anillin mutants reveals essential roles in septin localization and plasma membrane integrity.

Development (Cambridge, England) - 1 Jun 2005

Field Christine M, Coughlin Margaret, Doberstein Steve, Marty Thomas, Sullivan William

Abstract excerpt

Anillin is a conserved component of the contractile ring that is essential for cytokinesis, and physically interacts with three conserved cleavage furrow proteins, F-actin, myosin II and septins in biochemical assays. We demonstrate that the Drosophila scraps gene, identified as a gene involved in cellularization, encodes Anillin. We characterize defects in cellularization, pole cell formation and cytokinesis in...

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Identifiers

PMID: 15930114
DOI: 10.1242/dev.01843

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of anillin mutants reveals essential roles in septin localization and plasma membrane integrity.PMID 15930114Read ↗

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The chromosomal passenger complex and centralspindlin independently contribute to contractile ring assembly.Semantic proximity Read ↗

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Molecular dissection of cytokinesis by RNA interference in Drosophila cultured cells.Semantic proximity Read ↗

Cleavage furrow organization requires PIP(2)-mediated recruitment of anillin.Semantic proximity Read ↗

Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin networkSemantic proximity Read ↗

CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytiaSemantic proximity Read ↗

Anillin Phosphorylation Controls Timely Membrane Association and Successful Cytokinesis.Semantic proximity Read ↗

An anillin homologue, Mid2p, acts during fission yeast cytokinesis to organize the septin ring and promote cell separation.Semantic proximity Read ↗

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