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Article

Mutations in centrosomin reveal requirements for centrosomal function during early Drosophila embryogenesis.

Current biology : CB - 26 Aug 1999

Vaizel-Ohayon D, Schejter E D

Abstract excerpt

BACKGROUND: Although centrosomes serve as the primary organizing centers for the microtubule-based cytoskeleton in animal cells, various studies question the requirements for these organelles during the formation of microtubule arrays and execution of microtubule-dependent processes. Using a genetic approach to interfere with centrosomal function, we present an assessment of this issue, in the context of early...

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PMID: 10469591
DOI: 10.1016/s0960-9822(99)80393-5

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