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Article

New insights into the expression and role of platelet factor XIII-A.

Journal of thrombosis and haemostasis : JTH - 1 Jul 2009

Jayo A, Conde I, Lastres P, Jiménez-Yuste V, González-Manchón C

Abstract excerpt

BACKGROUND: The A subunit of factor XIII (FXIII-A) functions as an intracellular transglutaminase (TG) in the megakaryocyte/platelet lineage, where it probably participates in the cytoskeletal remodeling associated with cell activation. However, so far, the precise role of cellular FXIII (cFXIII) and the functional consequences of its absence in FXIII-A-deficient patients are unknown. OBJECTIVES AND METHODS: In...

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Identifiers

PMID: 19422454
DOI: 10.1111/j.1538-7836.2009.03456.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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