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Article

Platelet-delivered therapeutics.

Journal of thrombosis and haemostasis : JTH - 1 Jun 2015

Lyde R, Sabatino D, Sullivan S K, Poncz M

Abstract excerpt

We have proposed that modified platelets could potentially be used to correct intrinsic platelet defects as well as for targeted delivery of therapeutic molecules to sights of vascular injury. Ectopic expression of proteins within α-granules prior to platelet activation has been achieved for several proteins, including urokinase, factor (F) VIII, and partially for FIX. Potential uses of platelet-directed...

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Share to Blood Coagulation Disorders
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26149015
DOI: 10.1111/jth.12938

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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