Article
Inhibitory effects of TFPI variants on thrombin and factor Xa generation in fibrinogen-deficient human plasma.
Thrombosis research - 15 Dec 1994
Kaiser B, Jeske W, Hoppensteadt D, Fareed J
Abstract excerpt
Using a fast kinetic centrifugal analyzer, the inhibitory effects of glycosylated and unglycosylated full-length and truncated forms of TFPI on protease generation were studied in fibrinogen-deficient human plasma after extrinsic (EA) or intrinsic (IA) activation of coagulation. When the assay system was supplemented with increasing amounts of the TFPI variants the generation of both thrombin and factor Xa was...
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