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Article

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.

Blood - 2 Jul 2009

Abdel-Wahab Omar, Mullally Ann, Hedvat Cyrus, Garcia-Manero Guillermo, Patel Jay, Wadleigh Martha, Malinge Sebastien, Yao JinJuan, Kilpivaara Outi, Bhat Rukhmi, Huberman Kety, Thomas Sabrena, Dolgalev Igor, Heguy Adriana, Paietta Elisabeth, Le Beau Michelle M, Beran Miloslav, Tallman Martin S, Ebert Benjamin L, Kantarjian Hagop M, Stone Richard M, Gilliland D Gary, Crispino John D, Levine Ross L

Abstract excerpt

Disease alleles that activate signal transduction are common in myeloid malignancies; however, there are additional unidentified mutations that contribute to myeloid transformation. Based on the recent identification of TET2 mutations, we evaluated the mutational status of TET1, TET2, and TET3 in myeloproliferative neoplasms (MPNs), chronic myelomonocytic leukemia (CMML), and acute myeloid leukemia (AML)....

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Source

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Identifiers

PMID: 19420352
DOI: 10.1182/blood-2009-03-210039
PMCID: PMC2710942

Genes

TET2
TET1
TET3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.PMID 19420352Read ↗

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