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Article

TET2 mutations in cytogenetically normal acute myeloid leukemia: clinical implications and evolutionary patterns.

Genes, chromosomes & cancer - 1 Oct 2014

Damm Frederik, Markus Birgit, Thol Felicitas, Morgan Michael, Göhring Gudrun, Schlegelberger Brigitte, Krauter Jürgen, Heuser Michael, Bernard Olivier A, Ganser Arnold

Abstract excerpt

Mutations of the Ten-Eleven-Translocation 2 (TET2) gene have been identified in patients with various myeloid neoplasms, but the clinical relevance of these mutations and their timing during disease development in cytogenetically normal acute myeloid leukemia (CN-AML) remain unclear. The total coding region of TET2 was analyzed by direct sequencing in 215 CN-AML patients younger than 60 years from multicenter...

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Source

Identifiers

PMID: 24898826
DOI: 10.1002/gcc.22191

Genes

TET2
IDH1
NPM1
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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