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Article

Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.

Journal of thrombosis and haemostasis : JTH - 1 Nov 2010

Ken-Dror G, Drenos F, Humphries S E, Talmud P J, Hingorani A D, Kivimäki M, Kumari M, Bauer K A, Morrissey J H, Ireland H A

Abstract excerpt

BACKGROUND: Evidence for the associations of single nucleotide polymorphisms (SNPs) in the F7 gene and factor (F)VII levels and with risk of coronary heart disease (CHD) is inconsistent. We examined whether F7 tagging SNPs (tSNPs) and haplotypes were associated with FVII levels, coagulation activation markers (CAMs) and CHD risk in two cohorts of UK men. METHODS: Genotypes for eight SNPs and baseline levels of...

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Identifiers

PMID: 20735728
DOI: 10.1111/j.1538-7836.2010.04035.x
PMCID: PMC3226948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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