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Article

Use of Pharmacogenetic Information in the Treatment of Cardiovascular Disease.

Clinical chemistry - 1 Jan 2017

Friede Kevin, Li Josephine, Voora Deepak

Abstract excerpt

BACKGROUND: In 1964, Robert A. O'Reilly's research group identified members of a family who required remarkably high warfarin doses (up to 145 mg/day, 20 times the average dose) to achieve appropriate anticoagulation. Since this time, pharmacogenetics has become a mainstay of cardiovascular science, and genetic variants have been implicated in several fundamental classes of medications used in cardiovascular...

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Identifiers

PMID: 27864383
DOI: 10.1373/clinchem.2016.255232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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