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Article

Targeted mutations of transforming growth factor-beta genes reveal important roles in mouse development and adult homeostasis.

European journal of biochemistry - 1 Dec 2000

Dünker N, Krieglstein K

Abstract excerpt

Transforming growth factors-beta (TGF-beta) are multifunctional molecules with profound biological effects in many developmental processes including regulation of cell proliferation, differentiation, cell adhesion, skeletal development, haematopoiesis, inflammatory responses, and wound healing. To learn about the role of TGF-beta in vivo, phenotypes of targeted mutations of molecules within the TGF-beta...

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Source

Identifiers

PMID: 11106407
DOI: 10.1046/j.1432-1327.2000.01825.x

Genes

SMAD2
SMAD4
SMAD3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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