Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dysregulation of the immune response in TGF-β signalopathies

9 Dec 2022

Abstract excerpt

The transforming growth factor-β (TGF-β) family of cytokines exerts pleiotropic functions during embryonic development, tissue homeostasis and repair as well as within the immune system. Single gene defects in individual component of this signaling machinery cause defined Mendelian diseases associated with aberrant activation of TGF-β signaling, ultimately leading to impaired development, immune responses or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connective tissue disorders research
Share to Genetic factors in colorectal cancer
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36569843
DOI: 10.3389/fimmu.2022.1066375

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dysregulation of the immune response in TGF-β signalopathiesPMID 36569843Read ↗

TGF-β signaling in health and diseaseSemantic proximity Read ↗

TRANSFORMING GROWTH FACTOR-β REGULATION OF IMMUNE RESPONSESSemantic proximity Read ↗

The Love-Hate Relationship Between TGF-β Signaling and the Immune System During Development and TumorigenesisSemantic proximity Read ↗

TGFβ Superfamily Members as Regulators of B Cell Development and Function—Implications for AutoimmunitySemantic proximity Read ↗

Recent advances in understanding contextual TGFβ signalingSemantic proximity Read ↗

Targeted mutations of transforming growth factor-beta genes reveal important roles in mouse development and adult homeostasis.Semantic proximity Read ↗

Transforming Growth Factor-β: Master Regulator of the Respiratory System in Health and DiseaseSemantic proximity Read ↗

TGFβ signaling in cartilage development and maintenanceSemantic proximity Read ↗

Deficiencies and Dysregulation of STAT Pathways That Drive Inborn Errors of Immunity: Lessons from Patients and Mouse Models of Disease.Semantic proximity Read ↗

Immunoregulation by members of the TGFβ superfamilySemantic proximity Read ↗

Role of transforming growth factor-beta superfamily signaling pathways in human disease.Semantic proximity Read ↗

REGULATION OF IMMUNE RESPONSES BY TGF-βSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.