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Article

Overexpression of the transcription factor Foxo4 is associated with rapid glucose clearance.

Molecular and cellular endocrinology - 13 Aug 2009

Wang Biao, Zhu Jun, Mounzih Khalid, Chehab Eric F, Ke Yaohuang, Chehab Farid F

Abstract excerpt

Leptin treatment ameliorates lipoatrophic diabetes in animal models and humans. Transgenic mice overexpressing leptin (LepTg) are lipoatrophic but not diabetic and thus represent a model for elucidating mechanisms of leptin-mediated glucose homeostasis. In this communication, we show that LepTg mice overexpress the forkhead transcription factor foxo4 in their remnant adipose tissue. To further characterize the...

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Source

Identifiers

PMID: 19410631
DOI: 10.1016/j.mce.2009.04.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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