Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Forkhead transcription factor FoxO1 in adipose tissue regulates energy storage and expenditure.

Diabetes - 1 Mar 2008

Nakae Jun, Cao Yongheng, Oki Miyo, Orba Yasuko, Sawa Hirofumi, Kiyonari Hiroshi, Iskandar Kristy, Suga Koji, Lombes Marc, Hayashi Yoshitake

Abstract excerpt

OBJECTIVE: Adipose tissue serves as an integrator of various physiological pathways, energy balance, and glucose homeostasis. Forkhead box-containing protein O subfamily (FoxO) 1 mediates insulin action at the transcriptional level. However, physiological roles of FoxO1 in adipose tissue remain unclear. RESEARCH DESIGN AND METHODS: In the present study, we generated adipose tissue-specific FoxO1 transgenic mice...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Body Temperature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line

Share to Energy Metabolism

Share to Forkhead Box Protein O1

Share to Forkhead Transcription Factors

Share to Mice, Transgenic

Share to RNA Interference

Source

Identifiers

PMID: 18162510
DOI: 10.2337/db07-0698

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Forkhead transcription factor FoxO1 in adipose tissue regulates energy storage and expenditure.PMID 18162510Read ↗

Overexpression of the transcription factor Foxo4 is associated with rapid glucose clearance.Semantic proximity Read ↗

FoxO1 haploinsufficiency protects against high-fat diet-induced insulin resistance with enhanced peroxisome proliferator-activated receptor gamma activation in adipose tissue.Semantic proximity Read ↗

FoxO1 controls insulin-dependent adipose triglyceride lipase (ATGL) expression and lipolysis in adipocytes.Semantic proximity Read ↗

Exploring the Genetic Conception of Obesity via the Dual Role of FoxO.Semantic proximity Read ↗

The forkhead transcription factor Foxo1 regulates adipocyte differentiation.Semantic proximity Read ↗

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.Semantic proximity Read ↗

SIRT1 Regulates Adiponectin Gene Expression through Foxo1-C/Enhancer-binding Protein α Transcriptional ComplexSemantic proximity Read ↗

Understanding Forkhead Box Class O Function: Lessons from <i>Drosophila melanogaster</i>Semantic proximity Read ↗

Adipocyte RNA-binding protein CELF1 promotes beiging of white fat through stabilizing Dio2 mRNASemantic proximity Read ↗

FoxO1 Deacetylation Decreases Fatty Acid Oxidation in β-Cells and Sustains Insulin Secretion in Diabetes.Semantic proximity Read ↗

The Autophagy-related Gene 14 (Atg14) Is Regulated by Forkhead Box O Transcription Factors and Circadian Rhythms and Plays a Critical Role in Hepatic Autophagy and Lipid MetabolismSemantic proximity Read ↗

IRX3 Overexpression Enhances Ucp1 Expression In Vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.