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Article

p53: balancing tumour suppression and implications for the clinic.

European journal of cancer (Oxford, England : 1990) - 1 Sept 2009

Buganim Yosef, Rotter Varda

Abstract excerpt

It is well accepted today that cancer develops through a multi-step process that involves normal cells being led by well-defined phases into cancer cells. Along this process cells lose their natural cancer defence system that is mediated by tumour suppressor genes and accumulate genetic instabilities that permit the expression of the specific oncogenic networks. Remarkable is the p53 tumour suppressor which is...

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Identifiers

PMID: 19775621
DOI: 10.1016/S0959-8049(09)70037-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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