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Article

Characterization of the molecular defects in the mouse E beta f and E beta q genes. Implications for the origin of MHC polymorphism.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 1990

Begovich A B, Vu T H, Jones P P

Abstract excerpt

The E beta f and E beta q genes have been isolated and sequenced to investigate the molecular basis for their defective expression. A previous study from this laboratory, which characterized the expression of these genes at the RNA level, showed both genes to have defects in posttranscriptional RNA processing. In this paper, the defect in the E beta q gene from the inbred mouse strain B10.G (Mus musculus...

Topics

Amino Acid Sequence
Animals
Base Sequence
Biological Evolution
Genes
Genes, MHC Class II
Histocompatibility Antigens Class II
Major Histocompatibility Complex
Mice
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA Splicing

Restriction Mapping

Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 2106558

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2106558-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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