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Article

On the nature of peptides involved in T cell alloreactivity.

The Journal of experimental medicine - 1 Nov 1991

Rötzschke O, Falk K, Faath S, Rammensee H G

Abstract excerpt

The strong reaction of T cells against foreign major histocompatibility complex (MHC) antigens, commonly termed "alloreactivity", is not only a nuisance for clinical organ transplantation; it also remains a puzzling question for immunologists. By making use of recent technical developments, alloreactive T cells nominally directed against a mutation in a single MHC class I molecule were found to fall into several...

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Identifiers

PMID: 1940788
DOI: 10.1084/jem.174.5.1059
PMCID: PMC2118982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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On the nature of peptides involved in T cell alloreactivity.PMID 1940788Read ↗

The role of peptides in T cell alloreactivity is determined by self-major histocompatibility complex molecules.Semantic proximity Read ↗

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MHC-derived peptides and the CD4+ T-cell repertoire: implications for autoimmune disease.Semantic proximity Read ↗

CD8 expression alters the fine specificity of an alloreactive MHC class I-specific T hybridoma.Semantic proximity Read ↗

T cell reactivity to self and allogeneic MHC-peptides.Semantic proximity Read ↗

Alloreactive T cells discriminate among a diverse set of endogenous peptides.Semantic proximity Read ↗

A patient-derived cytotoxic T-lymphocyte clone and two peptide-dependent monoclonal antibodies recognize HLA-B27-peptide complexes with low stringency for peptide sequences.Semantic proximity Read ↗

Alloreactive cytotoxic T lymphocytes focus on specific major histocompatibility complex-bound peptides.Semantic proximity Read ↗

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Alloantibody production is regulated by CD4+ T cells' alloreactive pathway, rather than precursor frequency or Th1/Th2 differentiation.Semantic proximity Read ↗

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