Article
Alloreactive cytotoxic T lymphocytes focus on specific major histocompatibility complex-bound peptides.
Transplantation - 27 Jul 1997
Smith K D, Huczko E, Engelhard V H, Li Y Y, Lutz C T
Abstract excerpt
Alloreactive T cells are often specific for individual peptides that are bound to allogeneic major histocompatibility complex (MHC) molecules. Other alloreactive T cells are reported to be peptide-independent or to recognize MHC conformational changes that are induced by multiple peptides. We tested 12 anti-HLA-B7 alloreactive cytotoxic T lymphocyte (CTL) clones that bind a restricted region of HLA-B7, including...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
