Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The BRCA1 3'-UTR: 5711+421T/T_5711+1286T/T genotype is a possible breast and ovarian cancer risk factor.

Genetic testing and molecular biomarkers - 1 Jun 2009

Pongsavee Malinee, Yamkamon Vichanan, Dakeng Sumana, O-charoenrat Pornchai, Smith Duncan R, Saunders Grady F, Patmasiriwat Pimpicha

Abstract excerpt

BACKGROUND: A significant proportion of familial and early-onset breast and ovarian cancers occur in individuals without coding mutations of BRCA1 and BRCA2. AIMS: We identified genetic variation at 3'-untranslated region (UTR) of BRCA1 in familial and early-onset breast and ovarian cancer patients both with and without BRCA1/2 mutation in the coding regions (BRCA1/2 pos and BRCA1/2 neg), and verified the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to BRCA1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Genes, Reporter

Share to Heteroduplex Analysis

Share to Luciferases

Share to Ovarian Neoplasms

Share to Thailand

Source

Identifiers

PMID: 19405875
DOI: 10.1089/gtmb.2008.0127

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The BRCA1 3'-UTR: 5711+421T/T_5711+1286T/T genotype is a possible breast and ovarian cancer risk factor.PMID 19405875Read ↗

Rare BRCA1 haplotypes including 3'UTR SNPs associated with breast cancer risk.Semantic proximity Read ↗

Two novel variants in the 3'UTR of the BRCA1 gene in familial breast and/or ovarian cancer.Semantic proximity Read ↗

A Germline Mutation in the BRCA1 3’UTR Variant Predicts Susceptibility to Breast Cancer in a Saudi Arabian PopulationSemantic proximity Read ↗

rs15869 at miRNA binding site in BRCA2 is associated with breast cancer susceptibility.Semantic proximity Read ↗

Association of BRCA1 functional single nucleotide polymorphisms with risk of differentiated thyroid carcinoma.Semantic proximity Read ↗

Evaluation of genetic variations in miRNA-binding sites of BRCA1 and BRCA2 genes as risk factors for the development of early-onset and/or familial breast cancer.Semantic proximity Read ↗

Identification of a novel disease-associated variant in the BRCA1 3’UTR that introduces a functional miR-103 target siteSemantic proximity Read ↗

Identification and in silico analysis of functional SNPs of the BRCA1 gene.Semantic proximity Read ↗

The Difference in Contralateral Breast Cancer and Ovarian Cancer risks for BRCA1 Founder Variant (c.5266dup, c.4035del) Carriers with Primary Breast CancerSemantic proximity Read ↗

Two functional variations in 5'-UTR of hoGG1 gene associated with the risk of breast cancer in Chinese.Semantic proximity Read ↗

The BRCA1 and BRCA2 Genes in Early-Onset Breast Cancer Patients.Semantic proximity Read ↗

Reduced translation efficiency due to novel splicing variants in 5′ untranslated region and identification of novel cis-regulatory elements in canine and human BRCA2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.