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Article

Evaluation of genetic variations in miRNA-binding sites of BRCA1 and BRCA2 genes as risk factors for the development of early-onset and/or familial breast cancer.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Erturk Elif, Cecener Gulsah, Polatkan Volkan, Gokgoz Sehsuvar, Egeli Unal, Tunca Berrin, Tezcan Gulcin, Demirdogen Elif, Ak Secil, Tasdelen Ismet

Abstract excerpt

Although genetic markers identifying women at an increased risk of developing breast cancer exist, the majority of inherited risk factors remain elusive. Mutations in the BRCA1/BRCA2 gene confer a substantial increase in breast cancer risk, yet routine clinical genetic screening is limited to the coding regions and intron- exon boundaries, precluding the identification of mutations in noncoding and untranslated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25339023
DOI: 10.7314/apjcp.2014.15.19.8319

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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