Article

The Difference in Contralateral Breast Cancer and Ovarian Cancer risks for BRCA1 Founder Variant (c.5266dup, c.4035del) Carriers with Primary Breast Cancer

2024-11-01

Abstract excerpt

<h4>Introduction: </h4> Previous research has suggested, that primary breast cancer (PBC) and ovarian cancer (OC) risks can be modified by mutation location in BRCA1 gene. In this study we assessed and compared the risks of contralateral breast cancer (CBC) and OC after the event of PBC in carriers of regionally frequent BRCA1 founder pathogenic variants (PV) c.5266dup and c.4035del. Subjects and Methods: In the a...

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Literature Corpus work: d24bcb96-0645-5773-9b03-17976b94b5b1
DOI: 10.20944/preprints202411.0063.v1

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