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Article

Association of BRCA1 functional single nucleotide polymorphisms with risk of differentiated thyroid carcinoma.

Thyroid : official journal of the American Thyroid Association - 1 Jan 2012

Xu Li, Doan Phi C, Wei Qingyi, Liu Yanhong, Li Guojun, Sturgis Erich M

Abstract excerpt

BACKGROUND: Breast cancer 1, early onset (BRCA1) is a vital DNA repair gene, and the single nucleotide polymorphisms (SNPs) of this gene have been studied in diverse cancer types. In this study, we investigated the association between eight common BRCA1 functional SNPs and the risk of differentiated thyroid carcinoma (DTC). METHODS: This cancer center-based case-control study included 303 DTC cases and 511...

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Identifiers

PMID: 22136207
DOI: 10.1089/thy.2011.0117
PMCID: PMC3263304

Genes

BRCA1

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