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The BRCA1 and BRCA2 Genes in Early-Onset Breast Cancer Patients.

Advances in experimental medicine and biology - 1 Jan 2020

Saleem Mohamed, Ghazali Mohd Bazli, Wahab Md Azlan Mohamed Abdul, Yusoff Narazah Mohd, Mahsin Hakimah, Seng Ch'ng Ewe, Khalid Imran Abdul, Rahman Mohd Nor Gohar, Yahaya Badrul Hisham

Abstract excerpt

Approximately 5-10% of breast cancers are attributable to genetic susceptibility. Mutations in the BRCA1 and BRCA2 genes are the best known genetic factors to date. The goal of this study was to determine the structure and distribution of haplotypes of the BRCA1 and BRCA2 genes in early-onset breast cancer patients. We enrolled 70 patients diagnosed with early-onset breast cancer. A total of 21 SNPs (11 on BRCA1...

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Source

Identifiers

PMID: 29687286
DOI: 10.1007/5584_2018_147

Genes

BRCA1
BRCA2
AGT
TAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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