Article
Mitochondria and aging.
Advances in experimental medicine and biology - 1 Jan 2012
Lee Hsin-Chen, Wei Yau-Huei
Abstract excerpt
Aging is a degenerative process that is associated with progressive accumulation of deleterious changes with time, reduction of physiological function and increase in the chance of disease and death. Studies in several species reveal a wide spectrum of alterations in mitochondria and mitochondrial DNA (mtDNA) with aging, including (1) increased disorganization of mitochondrial structure, (2) decline in...
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