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Article

Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging.

Experimental biology and medicine (Maywood, N.J.) - 1 Oct 2002

Wei Yau-Huei, Lee Hsin-Chen

Abstract excerpt

Mitochondria do not only produce less ATP, but they also increase the production of reactive oxygen species (ROS) as by-products of aerobic metabolism in the aging tissues of the human and animals. It is now generally accepted that aging-associated respiratory function decline can result in enhanced production of ROS in mitochondria. Moreover, the activities of free radical-scavenging enzymes are altered in the...

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PMID: 12324649
DOI: 10.1177/153537020222700901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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