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Article

Accessibility of chromosomal recombination breaks in nuclei of wild-type and DNA-PKcs-deficient cells.

DNA repair - 4 Jul 2009

Franco Daniel, Chang Yung

Abstract excerpt

V(D)J recombination is a highly regulated process, proceeding from a site-specific cleavage to an imprecise end joining. After the DNA excision catalyzed by the recombinase encoded by recombination activating genes 1 and 2 (RAG1/2), newly generated recombination ends are believed held by a post-cleavage complex (PC) consisting of RAG1/2 proteins, and are subsequently resolved by non-homologous end joining (NHEJ)...

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Share to Chromosome Breakage
Share to DNA-Activated Protein Kinase
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 19395319
DOI: 10.1016/j.dnarep.2009.03.007
PMCID: PMC2703179

Genes

RAG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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