Article
Zinc-binding subunits of yeast RNA polymerases.
The Journal of biological chemistry - 15 Nov 1991
Treich I, Riva M, Sentenac A
Abstract excerpt
The zinc-binding subunits of yeast RNA polymerase A(I) and B(II) have been identified by a zinc-blotting technique. The two largest subunits of each enzyme (A190, A135, B220, and B150), as well as A12.2, A10, B44.5, B12.6, and B10, bind 65Zn(II). Predicted zinc-binding motifs have been noted in the NH2-terminal part of B220 and the COOH-terminal region of B150 subunits. Subdomains encompassing these motifs have...
Topics
- Base Sequence
- Binding Sites
- Binding, Competitive
- Cations, Divalent
- Cloning, Molecular
- Kinetics
- Macromolecular Substances
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Oligodeoxyribonucleotides
- Phenotype