Article
Gene RPA43 in Saccharomyces cerevisiae encodes an essential subunit of RNA polymerase I.
The Journal of biological chemistry - 13 Oct 1995
Thuriaux P, Mariotte S, Buhler J M, Sentenac A, Vu L, Lee B S, Nomura M
Abstract excerpt
Yeast RNA polymerase I contains 14 distinct polypeptides, including A43, a component of about 43 kDa. The corresponding gene, RPA43, encodes a 326-amino acid polypeptide matching the peptidic sequence of two tryptic fragments isolated from A43. Gene inactivation leads to a lethal phenotype that i...
Topics
- Amino Acid Sequence
- Electrophoresis, Agar Gel
- Genes, Fungal
- Macromolecular Substances
- Molecular Sequence Data
- Phenotype
- Plasmids
- Promoter Regions, Genetic
- Protein Conformation
- RNA Polymerase I
- RNA, Fungal
- RNA, Ribosomal
- Saccharomyces cerevisiae
- Species Specificity