Article
Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivo.
Nucleic acids research - 11 Dec 1994
Krämer A, Legrain P, Mulhauser F, Gröning K, Brosi R, Bilbe G
Abstract excerpt
A cDNA encoding the 60 kDa subunit of mammalian splicing factor SF3a has been isolated. The deduced protein sequence reveals a 30% identity to the PRP9 splicing protein of the yeast S.cerevisiae. The highest homology is present in a zinc finger-like region in the C-terminal domain of both protein...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA, Complementary
- Escherichia coli
- Fungal Proteins
- Genes
- Genes, Fungal
- HeLa Cells
- Humans
- Molecular Sequence Data
- Molecular Weight
- Mutation
- Phenotype
- RNA Splicing Factors