Article
Mutants in ABC10beta, a conserved subunit shared by all three yeast RNA polymerases, specifically affect RNA polymerase I assembly.
The Journal of biological chemistry - 26 Mar 1999
Gadal O, Shpakovski G V, Thuriaux P
Abstract excerpt
ABC10beta, a small polypeptide common to the three yeast RNA polymerases, has close homology to the N subunit of the archaeal enzyme and is remotely related to the smallest subunit of vaccinial RNA polymerase. The eucaryotic, archaeal, and viral polypeptides share an invariant motif CX2C. CC that is strictly essential for yeast growth, as shown by site-directed mutagenesis, whereas the rest of the ABC10beta...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
