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Article

Regional atrophy of transcallosal prefrontal connections in cognitively normal APOE epsilon4 carriers.

Journal of magnetic resonance imaging : JMRI - 1 May 2009

Filippini Nicola, Zarei Mojtaba, Beckmann Christian F, Galluzzi Samantha, Borsci Genoveffa, Testa Cristina, Bonetti Matteo, Beltramello Alberto, Ghidoni Roberta, Benussi Luisa, Binetti Giuliano, Frisoni Giovanni B

Abstract excerpt

PURPOSE: To investigate the possible effect of the APOE epsilon4 allele on age-related regional volume loss within the corpus callosum (CC) in healthy epsilon4 allele carriers compared with noncarriers. MATERIALS AND METHODS: A total of 211 subjects, ages 27 to 83 years, 51 epsilon4 carriers and 160 noncarriers underwent T1-weighted MRI scan. All subjects had normal MRI scan and performed within normal range on a...

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Source

Identifiers

PMID: 19388128
DOI: 10.1002/jmri.21757

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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