Article
PHF11 is not a major candidate gene for asthma or eczema in Chinese children.
Pediatric pulmonology - 1 Sept 2010
Sy Hing Y, Chan Iris H S, Hon Ellis K L, Kong Alice P S, Tang Nelson L S, Li Chung Y, Wong Gary W K, Waye Mary M Y, Lam Christopher W K, Chan Juliana C N, Leung Ting F
Abstract excerpt
SUMMARY: Positional cloning and candidate gene studies in different Caucasian populations identified the gene encoding plant homeodomain zinc finger protein 11 (PHF11) to be associated with asthma and eczema. Microarray analysis also confirmed increased PHF11 expression in type 1 T-helper lymphocytes. However, such disease associations are unclear in Asian subjects. This case-control genetic association study...
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