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Article

The PTGDR gene is not associated with asthma in 3 ethnically diverse populations.

The Journal of allergy and clinical immunology - 1 Dec 2006

Tsai Yuhjung J, Choudhry Shweta, Kho Jennifer, Beckman Kenneth, Tsai Hui-Ju, Navarro Daniel, Matallana Henry, Castro Richard A, Lilly Craig M, Nazario Sylvette, Rodriguez-Santana Jose R, Casal Jesus, Torres Alfonso, Salas Jorge, Chapela Rocio, Watson H George, Meade Kelley, Avila Pedro C, Rodriguez-Cintron William, LeNoir Michael, Burchard Esteban González

Abstract excerpt

BACKGROUND: The prostanoid DP receptor (PTGDR) gene on chromosome 14q22.1 has been identified as an asthma susceptibility gene. A haplotype with decreased transcription factor binding and transcription efficiency was associated with decreased asthma susceptibility in African American and white su...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17157653
DOI: 10.1016/j.jaci.2006.07.045

Genes

PTGDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17157653-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The PTGDR gene is not associated with asthma in 3 ethnically diverse populations.PMID 17157653Read ↗

PTGDR is not a major candidate gene for asthma and atopy in Chinese children.Semantic proximity Read ↗

Role of prostanoid DP receptor variants in susceptibility to asthma.Semantic proximity Read ↗

Functional haplotypes in the PTGDR gene fail to associate with asthma in two Australian populations.Semantic proximity Read ↗

Novel Genetic Risk factors for Asthma in African American Children: Precision Medicine and The SAGE II StudySemantic proximity Read ↗

Novel genetic risk factors for asthma in African American children: Precision Medicine and the SAGE II Study.Semantic proximity Read ↗

Association of PTGDR gene polymorphisms with asthma in two Caucasian populations.Semantic proximity Read ↗

Lack of association between three promoter polymorphisms of PTGDR gene and asthma in a Chinese Han population.Semantic proximity Read ↗

A meta-analysis of genome-wide association studies of asthma in Puerto Ricans.Semantic proximity Read ↗

PTGDR gene in asthma: a functional, genetic, and epigenetic study.Semantic proximity Read ↗

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ADAM33 is not associated with asthma in Puerto Rican or Mexican populations.Semantic proximity Read ↗

Con: Genome-wide association studies have not been useful in understanding asthma.Semantic proximity Read ↗

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