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Article

Pathogenetic significance of ecotropic viral integration site-1 in hematological malignancies.

Cancer science - 1 Jun 2009

Goyama Susumu, Kurokawa Mineo

Abstract excerpt

The ecotropic viral integration site-1 (Evi-1) gene was first identified as a common locus of retroviral integration in murine leukemia models. In humans, EVI-1 is located on chromosome 3q26, and rearrangements on chromosome 3q26 often activate EVI-1 expression in hematological malignancies. Overexpression of EVI-1 also occurs with high frequency in leukemia patients without 3q26 abnormalities, and importantly,...

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Source

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Identifiers

PMID: 19385966
DOI: 10.1111/j.1349-7006.2009.01152.x
PMCID: PMC11158526

Genes

GATA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Pathogenetic significance of ecotropic viral integration site-1 in hematological malignancies.PMID 19385966Read ↗

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