Article

Clinical Significance of Dynamic Monitoring of EVI1 Gene Expression in Pediatric Acute Myeloid Leukemia

2024-07-15

Abstract excerpt

<title>Abstract</title> <p>Objective To investigate the clinical significance of dynamic monitoring ecotropic virus integration site-1 (EVI1) expression in childhood acute myeloid leukemia (AML). Methods A retrospective analysis was conducted on 113 pediatric AML patients of Wuhan Children's Hospital from 2014 to 2022. The correlation between EVI1 expression levels and clinical indicators including clinical cha...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d77d8b4c-963d-5b7b-a90b-49d55a68a2c2
DOI: 10.21203/rs.3.rs-4490141/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Clinical Significance of Dynamic Monitoring of EVI1 Gene Expression in Pediatric Acute Myeloid LeukemiaDOI 10.21203/rs.3.rs-4490141/v1Read

EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemiaSemantic proximity Read

Low EVI1 expression at diagnosis predicted poor outcomes in pediatric Ph-negative B cell precursor acute lymphoblastic leukemia patientsSemantic proximity Read

Global Identification of EVI1 Target Genes in Acute Myeloid LeukemiaSemantic proximity Read

High EVI1 Expression Predicts Poor Outcomes in Adult Acute Myeloid Leukemia Patients with Intermediate Cytogenetic Risk Receiving ChemotherapySemantic proximity Read

[EVI1 expression, clinical and cytogenetical characteristics in 447 patients with acute myeloid leukemia].Semantic proximity Read

EVI1 dysregulation: impact on biology and therapy of myeloid malignancies.Semantic proximity Read

High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AMLSemantic proximity Read

High <i> <scp>EVI</scp> 1 </i> expression is associated with <i> <scp>MLL</scp> </i> rearrangements and predicts decreased survival in paediatric acute myeloid leukaemia: a report from the children's oncology groupSemantic proximity Read

High EVI1 expression predicts outcome in younger adult patients with acute myeloid leukemia and is associated with distinct cytogenetic abnormalities.Semantic proximity Read

EVI1-mediated Programming of Normal and Malignant HematopoiesisSemantic proximity Read

High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimatedSemantic proximity Read

EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environmentSemantic proximity Read