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Article

Telomere maintenance and survival in saccharomyces cerevisiae in the absence of telomerase and RAD52.

Genetics - 1 Jul 2009

Lebel Catherine, Rosonina Emanuel, Sealey David C F, Pryde Fiona, Lydall David, Maringele Laura, Harrington Lea A

Abstract excerpt

Telomeres are essential features of linear genomes that are crucial for chromosome stability. Telomeric DNA is usually replenished by telomerase. Deletion of genes encoding telomerase components leads to telomere attrition with each cycle of DNA replication, eventually causing cell senescence or death. In the Saccharomyces cerevisiae strain W303, telomerase-null populations bypass senescence and, unless EXO1 is...

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Source

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Identifiers

PMID: 19380905
DOI: 10.1534/genetics.109.102939
PMCID: PMC2710150

Genes

RAD52
EXO1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Telomere maintenance and survival in saccharomyces cerevisiae in the absence of telomerase and RAD52.PMID 19380905Read ↗

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