Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Replication stress as a source of telomere recombination during replicative senescence inSaccharomyces cerevisiae

27 Sept 2016

Abstract excerpt

Replicative senescence is triggered by short unprotected telomeres that arise in the absence of telomerase. In addition, telomeres are known as difficult regions to replicate due to their repetitive G-rich sequence prone to secondary structures and tightly bound non-histone proteins. Here we review accumulating evidence that telomerase inactivation in yeast immediately unmasks the problems associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair Mechanisms
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27683094
DOI: 10.1093/femsyr/fow085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replication stress as a source of telomere recombination during replicative senescence inSaccharomyces cerevisiaePMID 27683094Read ↗

Saccharomyces cerevisiae as a Model to Study Replicative Senescence Triggered by Telomere ShorteningSemantic proximity Read ↗

Roles of Telomere Biology in Cell Senescence, Replicative and Chronological AgeingSemantic proximity Read ↗

Portrait of replication stress viewed from telomeres.Semantic proximity Read ↗

Unravelling the Intricacies of Telomere Replication: A Molecular ConundrumSemantic proximity Read ↗

Tieing together loose ends: telomere instability in cancer and agingSemantic proximity Read ↗

Multiple genetic pathways regulate replicative senescence in telomerase-deficient yeast.Semantic proximity Read ↗

ALTercations at telomeres: stress, recombination and extrachromosomal affairsSemantic proximity Read ↗

Reversibility of replicative senescence in Saccharomyces cerevisiae: effect of homologous recombination and cell cycle checkpoints.Semantic proximity Read ↗

Telomere-Telomere Recombination Is an Efficient Bypass Pathway for Telomere Maintenance in <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand BreaksSemantic proximity Read ↗

Telomeres, telomerase and senescence.Semantic proximity Read ↗

Telomere maintenance and survival in saccharomyces cerevisiae in the absence of telomerase and RAD52.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.