Article
Association analysis between the prostaglandin E synthase 2 R298H polymorphism and body mass index in 8079 participants of the KORA study cohort.
Genetic testing and molecular biomarkers - 1 Apr 2009
Fischer Alexandra, Grallert Harald, Böhme Mike, Gieger Christian, Boomgaarden Inka, Heid Iris, Wichmann H-Erich, Döring Frank, Illig Thomas
Abstract excerpt
CONTEXT: The H-allele of the R298H polymorphism in the prostaglandin E synthase 2 (PTGES2) gene was associated with lower risk of diabetes type 2. AIM: To explore the association between the PTGES2 R298H SNP and body mass index (BMI). METHODS: We analyzed the R298H SNP (rs13283456) and three haplotype single-nucleotide polymorphisms (rs884115, rs10987883, and rs4837240) covering a 20 kb gene region in...
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