Article
Prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism and parameters of the metabolic syndrome.
Molecular nutrition & food research - 1 Dec 2007
Lindner Inka, Helwig Ulf, Rubin Diana, Fischer Alexandra, Marten Berit, Schreiber Stefan, Döring Frank, Schrezenmeir Jürgen
Abstract excerpt
The prostaglandin E synthase 2 (PTGES2) gene maps to a locus linked to obesity and is involved in the synthesis of the antilipolytic compound prostaglandin E(2). In a recent study, we found an association of the minor PTGES2 Arg298His allele and lower risk of type 2 diabetes mellitus in the European Investigation into Cancer and Nutrition (EPIC) and Cooperative Health Research in the Augsburg Region (KORA)...
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