Article
Haplotype structure of the beta2-adrenergic receptor gene in 814 Danish Caucasian subjects and association with body mass index.
Scandinavian journal of clinical and laboratory investigation - 1 Jan 2009
Jensen Mette Kamp, Nielsen Morten, Koefoed Pernille, Nielsen Henning Bay, Ullum Henrik, Haastrup Eva, Romner Bertil, Moltke Finn Borgbjerg, Olsen Niels Vidiendal
Abstract excerpt
Several single nucleotide polymorphisms (SNPs) have been identified in the beta(2)-adrenergic receptor gene (ADRB2). By the use of five SNPs (G46A, C79G, C491T, C523A, G1053C) for identification of ADRB2 haplotypes in 814 Danish Caucasians, we investigated whether ADRB2 haplotypes are associated with body mass index (BMI). The SNPs showed organization into 13 distinct haplotypes and 41 haplotype pairs. The study...
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