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Article

The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children.

BMC medical genetics - 17 May 2012

Rask-Andersen Mathias, Jacobsson Josefin A, Moschonis George, Ek Anna E, Chrousos George P, Marcus Claude, Manios Yannis, Fredriksson Robert, Schiöth Helgi B

Abstract excerpt

BACKGROUND: Recent genome-wide association studies have identified a single nucleotide polymorphism within the last intron of MAP2K5 associated with a higher body mass index (BMI) in adults. MAP2K5 is a component of the MAPK-family intracellular signaling pathways, responding to extracellular growth factors such as brain derived neurotrophic factor (BDNF) and nerve growth factor (NGF). In this study, we examined...

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PMID: 22594783
DOI: 10.1186/1471-2350-13-36
PMCID: PMC3459804

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BDNF
NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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