Article
RGS2 C1114G polymorphism and body weight gain in hypertensive patients.
Metabolism: clinical and experimental - 1 Mar 2008
Sartori Michelangelo, Ceolotto Giulio, Dorigatti Francesca, Mos Lucio, Santonastaso Massimo, Bratti Paolo, Papparella Italia, Semplicini Andrea, Palatini Paolo
Abstract excerpt
RGS2 is a negative regulator of Galpha protein signaling and promotes adipocyte differentiation. Recently, we described a polymorphism at the C1114G locus with the G allele associated with hypertension in a cross-sectional study. The aim of the present study was to assess whether the RGS2 C1114G is predictive of overweight in young subjects with grade I hypertension. We genotyped at the RGS2 C1114G locus 406...
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