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Article

Complex phenotypes and phenomenon of genome-wide inter-chromosomal linkage disequilibrium in the human genome.

Experimental gerontology - 1 Dec 2011

Kulminski Alexander M

Abstract excerpt

Studies of non-human species show that loci on non-homologous chromosomes can be in linkage disequilibrium (LD). I focus on the Framingham Heart Study (FHS) participants to explore whether the phenomenon of inter-chromosomal LD can be caused by non-stochastic bio-genetic mechanisms in the human genome and be associated with complex, polygenic phenotypes. This paper documents remarkably strong and extensive LD...

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PMID: 21907271
DOI: 10.1016/j.exger.2011.08.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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